Our company, the Mainz Scientific Screening Center UG (haftungsbeschränkt) & Co. KG, was founded in 2014 in Mainz, Germany.

The company is headed by the biologist Prof. Dr. phil. nat. Shirley Knauer, born in 1976, Ph.D. in Pharmaceutical Biology, habilitation in Molecular Medicine, Professor of Molecular Biology at the University of Duisburg-Essen (department head since 2010).

Our main partner and customer is the University Mainz Medical Center, for which we i.a. organize the annual ChemBioMed symposia.

calendarour ComPEtence


Equipped with the long-standing expertise of developing and adapting cell-based assay systems for medium- to high-throughput screening applications, we are able to provide you with a wide variety of established test systems and biological read-outs.

Moreover, we design novel tailor-made assays to be adapted on our screening platform according to the customers' request within a reasonable time frame.


Reference Publications


Wünsch, D., Hahlbrock, A., Heiselmayer, C., Backer, S., Heun, P., Goesswein, D., Stöcker, W., Schirmeister, T., Schneider, G., Krämer, O.H., Knauer, S.K., Stauber, R.H., 2015. Fly versus man: Evolutionary impairment of nucleolar targeting affects the degradome of Drosophila's Taspase1. Faseb J.


Docter, D., Distler, U., Storck, W., Kuharev, J., Wünsch, D., Hahlbrock, A., Knauer, S.K., Tenzer, S., Stauber, R.H., 2014. Quantitative profiling of the protein coronas that form around nanoparticles. Nature Protocols 9, 2030-2044.

Stolte, S., Ha, T., Steudte, S., Korinth, V., Arning, J., Białk-Bielińska, A., Bottin-Weber, U., Cokoja, M., Fetz, V., Hahlbrock, A., Stauber, R.H., Jastorff, B., Hartmann, C., Fischer, R., Kühn, F.E., 2014. Preliminary Toxicity and Ecotoxicity Assessment of Methyltrioxorhenium and Derivatives. Green Chemistry, DOI: 10.1039/C1034GC01919A.


Tenzer, S., Docter, D., Kuharev, J., Musyanovych, A., Fetz, V., Hecht, R., Schlenk, F., Fischer, D., Kiouptsi, K., Reinhardt, C., Landfester, K., Schild, H., Maskos, M., Knauer, S.K., Stauber, R.H., 2013. Rapid formation of plasma protein corona critically affects nanoparticle pathophysiology. Nature Nanotechnology 8, 772-781.


Stauber, R.H., Bier, C., Knauer, S.K., 2012. Targeting Taspase1 for cancer therapy. Cancer Research 72, 2912.

Bier, C., Knauer, S.K., Wunsch, D., Kunst, L., Scheiding, S., Kaiser, M., Ottmann, C., Krämer, O.H., Stauber, R.H., 2012. Allosteric inhibition of Taspase1's pathobiological activity by enforced dimerization in vivo. Faseb J 26, 3421-3429.


Knauer, S.K., Heinrich, U.R., Bier, C., Habtemichael, N., Docter, D., Helling, K., Mann, W.J., Stauber, R.H., 2010. An otoprotective role for the apoptosis inhibitor protein survivin. Cell Death and Disease 1, e51.



Please get in touch via our contact page.

Alternatively you can email us direct here.

You can also call us 9-5 Monday to Friday at the following phone number: +49 (0) 160 96904644.

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